Job Description

The Gladstone Institutes is a premier, independent, not-for-profit biomedical research organization dedicated to advancing human health through cutting-edge science and transformative education. Our interdisciplinary research spans neuroscience, cardiovascular disease, immunology, and stem cell biology, with a mission to uncover the molecular underpinnings of disease and discover new therapeutic approaches. Located in a world-class facility at the Mission Bay Campus, Gladstone fosters a dynamic and collaborative environment where innovation thrives. Our community includes over 600 scientists, trainees, and staff—many of whom are internationally recognized leaders in their fields. We offer competitive compensation, excellent benefits, and the resources to support both professional development and impactful scientific discovery. The Conklin Lab is part of Gladstone’s pioneering efforts in human therapeutic genome editing, with a strong focus on DNA repair mechanisms. Working in close partnership with the Innovative Genomics Institute, our lab applies advanced molecular biology techniques and cellular models to explore new strategies for correcting genetic defects. For more information, visit We are seeking a Research Associate I to support ongoing projects focused on DNA repair and genome editing, particularly using motor neurons as a model system. This role offers a unique opportunity to work at the forefront of molecular and cellular biology and contribute to high-impact translational research. Responsibilities include conducting experiments to study the basic mechanisms of DNA repair, performing DNA excision assays and related molecular techniques in cell culture systems, utilizing motor neurons derived from stem cells as a disease-relevant model, maintaining and differentiating human cell lines including iPSC-derived neurons, analyzing and documenting experimental data, assisting with interpretation and presentation, collaborating with team members across projects, contributing to lab meetings and discussions, and ensuring compliance with lab protocols, safety standards, and institutional guidelines. Requirements include a Bachelor’s degree (BA/BS) in Biology, Molecular Biology, Genetics, or a related discipline (preferred), prior experience working in a biological research laboratory (required), familiarity with molecular biology techniques such as PCR, DNA/RNA extraction, gel electrophoresis, and cloning (preferred), experience with cell culture especially human or stem cell-derived lines (preferred), excellent written and verbal communication skills, detail-oriented, highly organized, capable of working independently or in a team environment, and a strong interest in genome editing and human disease modeling. Individuals intending to pursue graduate studies in biomedical sciences are strongly encouraged to apply.

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